Detalhe da pesquisa
1.
Teixobactin kills bacteria by a two-pronged attack on the cell envelope.
Nature
; 608(7922): 390-396, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35922513
2.
Probing differences among Aß oligomers with two triangular trimers derived from Aß.
Proc Natl Acad Sci U S A
; 120(22): e2219216120, 2023 05 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37216514
3.
ß-Hairpin Alignment Alters Oligomer Formation in Aß-Derived Peptides.
Biochemistry
; 63(2): 212-218, 2024 Jan 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38163326
4.
Amyloid-α Peptide Formed through Alternative Processing of the Amyloid Precursor Protein Attenuates Alzheimer's Amyloid-ß Toxicity via Cross-Chaperoning.
J Am Chem Soc
; 146(4): 2634-2645, 2024 Jan 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-38236059
5.
Supramolecular Interactions of Teixobactin Analogues in the Crystal State.
J Org Chem
; 89(7): 5104-5108, 2024 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38506062
6.
A turn for the worse: Aß ß-hairpins in Alzheimer's disease.
Bioorg Med Chem
; 105: 117715, 2024 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38615460
7.
Synthesis and Stereochemical Determination of the Peptide Antibiotic Novo29.
J Org Chem
; 88(4): 2214-2220, 2023 02 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36655882
8.
Effects of Familial Alzheimer's Disease Mutations on the Assembly of a ß-Hairpin Peptide Derived from Aß16-36.
Biochemistry
; 61(6): 446-454, 2022 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35213141
9.
A Disulfide-Stabilized Aß that Forms Dimers but Does Not Form Fibrils.
Biochemistry
; 61(4): 252-264, 2022 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35080857
10.
Expression of N-Terminal Cysteine Aß42 and Conjugation to Generate Fluorescent and Biotinylated Aß42.
Biochemistry
; 60(15): 1191-1200, 2021 04 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33793198
11.
An Improved Turn Structure for Inducing ß-Hairpin Formation in Peptides.
Angew Chem Int Ed Engl
; 60(42): 22776-22782, 2021 10 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34258835
12.
Phenylalanine Mutation to Cyclohexylalanine Facilitates Triangular Trimer Formation by ß-Hairpins Derived from Aß.
J Am Chem Soc
; 142(49): 20708-20716, 2020 12 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33237748
13.
Interpenetrating Cubes in the X-ray Crystallographic Structure of a Peptide Derived from Medin19-36.
J Am Chem Soc
; 142(37): 15870-15875, 2020 09 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-32816461
14.
Effects of N-Terminal Residues on the Assembly of Constrained ß-Hairpin Peptides Derived from Aß.
J Am Chem Soc
; 142(26): 11593-11601, 2020 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32501687
15.
Anaphylaxis Induced by Peptide Coupling Agents: Lessons Learned from Repeated Exposure to HATU, HBTU, and HCTU.
J Org Chem
; 85(3): 1764-1768, 2020 02 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31849224
16.
Design, Synthesis, and Study of Lactam and Ring-Expanded Analogues of Teixobactin.
J Org Chem
; 85(3): 1331-1339, 2020 02 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31746604
17.
Correction to "ß-Hairpin Alignment Alters Oligomer Formation in Aß-Derived Peptides".
Biochemistry
; 63(5): 723, 2024 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38360534
18.
Elucidating the Structures of Amyloid Oligomers with Macrocyclic ß-Hairpin Peptides: Insights into Alzheimer's Disease and Other Amyloid Diseases.
Acc Chem Res
; 51(3): 706-718, 2018 03 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29508987
19.
An Efficient Method for the Expression and Purification of Aß(M1-42).
Biochemistry
; 57(26): 3861-3866, 2018 07 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29757632
20.
Structural Polymorphs Suggest Competing Pathways for the Formation of Amyloid Fibrils That Diverge from a Common Intermediate Species.
Biochemistry
; 57(46): 6470-6478, 2018 11 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-30375231